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. 2023 Jul 7;23:303. doi: 10.1186/s12886-023-03021-0

Table 1.

Baseline demographic and clinical characteristics for patients who developed sequential neovascular age-related macular degeneration

Characteristic
Age at diagnosis, years
 First eye, mean (SD) 81.6 (8.0)
  Median (range) 83 (60–94)
 Second eye, mean (SD) 82.8 (8.1)
  Median (range) 84 (60–96)
Sex, n (%)
 Female 34 (65.4)
Race, n (%)
 White (non-Hispanic) 50 (96.1)
First treated eye, n (%)
 Right eye 25 (48.1)

Time between diagnosis of the

first and second eye, days

 Mean (SD) 440 (328)
 Median (range) 362 (32–1356)

Disease severity in fellow eye

at first eye diagnosis, n (%)

 Early 12 (23.1)
 Intermediate 36 (69.2)
 Advanced 4 (7.7)
Sociomedical characteristic, n (%)
 Nutritional supplement use1 38 (73.1)2
 Active smoker 2 (3.8)
 Former smoker 16 (30.8)
 No smoking history 34 (65.4)
 Family history of AMD 18 (34.6)

1Includes use of Age-Related Eye Disease Study (AREDS) and/or AREDS 2 vitamins, or their equivalent. 2Two additional Patients started AREDS 2 vitamins by the time of second eye conversion