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. 2023 Jul 7;23:303. doi: 10.1186/s12886-023-03021-0

Table 2.

Clinical characteristics and anatomical outcomes at diagnosis and at one year for eyes diagnosed with sequential neovascular age-related macular degeneration

Characteristic Groups
First Eye Second Eye P-value 1
VA, logMAR (SD)
 At diagnosis 0.68 (0.51) 0.41 (0.34) 0.002 2
 At 12 months 0.61 (0.60) 0.42 (0.37) 0.041 2
  P-value1 0.241 2 0.872 2
CMT, µm (SD)
 At diagnosis 340 (92) 311 (73) 0.0792
 At 12 months 272 (57) 265 (53) 0.4672
  P-value1 <0.0012 <0.0012
Hemorrhage, n (%)
 At diagnosis 10 (19.2) 6 (11.5) 0.4163
 At 12 months 1 (1.9) 3 (5.8) 0.6183
  P-value1 0.008 3 0.488 3
IRF, n (%)
 At diagnosis 31 (59.6) 37 (71.2) 0.2164
 At 12 months 26 (50.0) 27 (51.9) 0.8454
  P-value1 0.325 4 0.044 4
SRF, n (%)
 At diagnosis 42 (80.8) 16 (30.8) <0.001 4
 At 12 months 17 (32.7) 17 (32.7) 1.00 4
  P-value1 <0.0014 0.833 4
PED, n (%)
 At diagnosis 47 (90.4) 46 (88.5) 0.750 4
 At 12 months 44 (84.6) 44 (84.6)  1.004
  P-value1 0.374 4  0.5664
PED, µm (SD)
 At diagnosis 225 (176) 155 (144) 0.003 5
 At 12 months 188 (137) 140 (112)  0.0194
  P-value1 0.322 5  0.9285

1Significance is marked in bold (P < 0.05). 2Student’s t-test. 3Fisher exact test. 4Chi–square test. 5Mann–Whitney U test