Table 4.
Multivariate-adjusted HRs (95%CI) of HDL-c, LDL-c, TG, TyG index, FPG, 1h-PG and 2h-PG for incidence of T2DM at 20 years of follow-up.
| Variables | Non-adjusted HR (95% CI) a |
P | Age-adjusted HR (95% CI) a |
P | Multivariate
b
HR (95% CI) a |
P |
|---|---|---|---|---|---|---|
| HDL-c, mmol/L | ||||||
| ≥1.0 | 1 | 1 | 1 | |||
| <1.0 | 1.462 (1.197-1.786) | <0.001 | 1.410 (1.154-1.723) | 0.001 | 1.421 (1.163-1.737) | 0.001 |
| LDL-c, mmol/L | ||||||
| <3.4 | 1 | 1 | 1 | |||
| ≥3.4 | 1.217 (1.028-1.441) | 0.023 | 1.201 (1.015-1.422) | 0.033 | 1.232 (1.040-1.459) | 0.016 |
| TG, mmol/L | ||||||
| <1.7 | 1 | 1 | ||||
| ≥1.7 | 1.411 (1.192-1.670) | <0.001 | 1.459 (1.232-1.728) | <0.001 | 1.400 (1.180-1.660) | <0.001 |
| TyG index | ||||||
| T1 | 1 | 1 | 1 | |||
| T2 | 1.451 (1.170-1.799) | 0.001 | 1.503 (1.212-1.864) | <0.001 | 1.457 (1.174-1.808) | 0.001 |
| T3 | 1.702 (1.377-2.103) | <0.001 | 1.800 (1.455-2.227) | <0.001 | 1.704 (1.375-2.111) | <0.001 |
| FPG, mmol/L | ||||||
| ≤6 | 1 | 1 | 1 | |||
| >6 | 2.105 (1.505-2.943) | <0.001 | 2.152 (1.539-3.009) | <0.001 | 2.036 (1.454-2.851) | <0.001 |
| 1h-PG | ||||||
| T1 | 1 | 1 | 1 | |||
| T2 | 1.821 (1.436-2.310) | <0.001 | 1.798 (1.417-2.280) | <0.001 | 1.802 (1.421-2.285) | <0.001 |
| T3 | 4.335 (3.464-5.425) | <0.001 | 4.242 (3.388-5.311) | <0.001 | 4.150 (3.314-5.199) | <0.001 |
| 2h-PG, mmol/L | ||||||
| <7.8 | 1 | 1 | 1 | |||
| ≥7.8 | 2.840 (2.394-3.370) | <0.001 | 2.747 (2.313-3.264) | <0.001 | 2.754 (2.318-3.273) | <0.001 |
HR, hazard ratio; CI, confidence interval; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; TG, triglyceride; TyG index, triglyceride fasting glucose index; FPG, fasting plasma glucose; 1h-PG, 1-hour plasma glucose concentration; 2h-PG, 2-hour plasma glucose concentration.
a
HR=1 as reference level.
b
variables were age, BMI, WC, SBP and hypertension.