Table 5.
Multivariate-adjusted HRs (95%CI) and C-index of TyG index, FPG, 1h-PG, 2h-PG, HDL-c, LDL-c, TC and TG for incidence of T2DM at 20 years of follow-up.
| Variables | Non-adjusted HR (95% CI) |
P | C-index | P a | Multivariate
b
HR (95% CI) |
P | C-index | P a |
|---|---|---|---|---|---|---|---|---|
| TyG index | 1.538 (1.307-1.810) | <0.001 | 0.570 | Ref. | 1.525 (1.290-1.804) | <0.001 | 0.623 | Ref. |
| FPG | 1.366 (1.193-1.563) | <0.001 | 0.557 | 0.366 | 1.350 (1.181-1.544) | <0.001 | 0.617 | 0.591 |
| 1h-PG | 1.364 (1.309-1.420) | <0.001 | 0.688 | <0.001 | 1.337 (1.282-1.395) | <0.001 | 0.704 | 0.001 |
| 2h-PG | 1.452 (1.375-1.533) | <0.001 | 0.680 | <0.001 | 1.401 (1.327-1.480) | <0.001 | 0.694 | <0.001 |
| HDL-c | 0.453 (0.338-0.609) | <0.001 | 0.594 | 0.175 | 0.505 (0.375-0.681) | <0.001 | 0.631 | 0.106 |
| LDL-c | 1.036 (0.941-1.141) | 0.490 | – | – | 1.049 (0.951-1.156) | 0.341 | – | – |
| TC | 1.015 (0.924-1.114) | 0.778 | – | – | 1.034 (0.942-1.136) | 0.479 | – | – |
| TG | 1.126 (1.060-1.196) | <0.001 | 0.558 | 0.005 | 1.120 (1.053-1.192) | <0.001 | 0.610 | 0.125 |
HR, hazard ratio; CI, confidence interval; TyG index, triglyceride fasting glucose index; FPG, fasting plasma glucose; 1h-PG, 1-hour plasma glucose concentration; 2h-PG, 2-hour plasma glucose concentration; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglyceride.
a
P value are the comparisons of C-index for the model including TyG index vs C-index for models including other variables.
b
Included variables were age, BMI, WC, SBP and hypertension.
-, not applicable.