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. 2023 Jun 23;10:1193121. doi: 10.3389/fmed.2023.1193121

Table 2.

Associations of parameters of endothelial dysfunction and SSc-specific clinical changes with vitamin D deficiency and insufficiency.

25-(OH)-D < 20 ng/ml 25-(OH)-D < 30 ng/ml
FMD < 7% 0.736 0.593
NMD < 15.6% 0.592 0.171
PWV > 10 m/s 0.357 0.472
Present sclerodactylyl 0.871 0.743
Present telangiectasia 0.740 0.351
Present puffy finger 0.046 0.544
Early pattern 0.040 0.472
Active pattern 0.906 0.459
Late pattern 0.611 0.858
Mild periodontitis 0.176 0.326
Severe periodontitis 0.292 0.536
EUSTAR index ≥2.5 0.368 0.629

Asymptotic p-values of chi-square test. 25-(OH)-D, 25-hydroxyvitamin D3; EUSTAR, European Scleroderma Trials and Research Group; FMD, flow-mediated dilation; NMD, nitroglycerin-mediated dilation; PWV, pulse-wave velocity.