Table 2.
Fusion transcripts involving ALK in ALK-positive anaplastic large cell lymphoma.
| Fusion | Translocation | Immunostaining |
|---|---|---|
| NPM1_ALK ( 90) | t (2,5)(p23.2;q35.1) | Nuclear and cytoplasmic |
| TPM3_ALK ( 91) | t(1;2)(q25;p23) | Cytoplasmic with peripheric reinforcement |
| ATIC_ALK ( 92) | inv(2)(p23q35) | Cytoplasmic diffuse |
| TFG_ALK ( 93) | t(2;3)(p23;q12.2) | Cytoplasmic diffuse |
| CLTCL_ALK ( 94) | t(2;17)(p23;q23) | Cytoplasmic granular |
| MSN_ALK ( 95) | t(X;2)(q11-12;p23) | Membranous |
| ALO17_ALK ( 96) | t(2;17)(p23;q25) | Cytoplasmic diffuse |
| MYH9_ALK ( 97) | t(2;22)(p23;q11.2) | Cytoplasmic diffuse |
| TRAF1_ALK ( 87) | t(2;9)(p23;q33) | Cytoplasmic |
| EEF1G_ALK ( 98) | t(2;11)(p23;q12.3) | Cytoplasmic |
| PABPC1_ALK ( 99) | t(2;8)(p23;q22) | Cytoplasmic |