Figure 6.

HucMSC-Exos decreases IL-1β and IL-18 secretion by BV2 cells and prevents the adoption of pyroptosis-associated morphology by BV2 cells.

(A) The effect of Exos on IL-1β and IL-18 secretion by BV2 cells was assayed by enzyme-linked immunosorbent assay. (B) The effect of Exos on BV2 cell morphology as observed by scanning electron microscopy. The arrow indicates pyroptotic cells. Scale bars: 2 μm. All data are shown by mean ± SD. ***P < 0.001 (n = 4; one-way analysis of variance followed by least significant difference test). ATP: Adenosine triphosphate; ELISA: Enzyme-linked immunosorbent assay; Exos: exosomes; hucMSCs-Exos: human umbilical cord mesenchymal stem cells derived exosomes; IL-18: interleukin-18; IL-1β: interleukin-1β; LPS: lipopolysaccharide.Ibeatem exerchici andi conse velessi id esequi dist mo et re pro temporum quidipsam et