Table 1.
Group | n | Microglia response |
---|---|---|
Control | 4 | • |
6-OHDA | 4 | + + + |
+ + + | ||
+ + | ||
+ + + | ||
Exos-T | 4 | + |
+ | ||
+ + | ||
+ | ||
Exos-LV | 4 | + + |
+ | ||
+ | ||
+ |
Baseline “resting” morphology (•), and mild (+), moderate (+ +), and intense responses (+ + +); Exos-T and Exos-LV indicate the 6-OHDA-induced PD model treated with Exos injection through the tail or lateral ventricle, respectively. All scores pertain to the lesioned side. 6-OHDA: 6-Hydroxydopamine; Exos: exosomes; SN: substantia nigra.