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. Author manuscript; available in PMC: 2023 Sep 1.
Published in final edited form as: Addict Neurosci. 2023 Apr 2;7:100085. doi: 10.1016/j.addicn.2023.100085

Table 2.

Differences in BOLD responses associated with Naltrexone versus Placebo conditions.

Cluster size (k) Peak Region MNI coordinates
t-score p-value (FWE) Cohen’s d
x y z
Positive Regions
25 L Caudate −12 1 13 7.26 0.000 1.67
−1 −2 −1 5.87 0.001 1.35
18 R Caudate 9 8 3 6.68 0.000 1.53
13 5 13 5.82 0.002 1.34
10 R Thalamus 9 −13 7 6.41 0.000 1.47
16 −2 20 5.12 0.030 1.17
12 R Cerebellum 30 −41 −32 6.36 0.000 1.46
34 −48 −36 5.85 0.001 1.34
15 R Sensorimotor 44 −23 41 6.33 0.000 1.45
x R Cerebellum 20 −72 −22 6.18 0.000 1.42
16 −72 −36 5.41 0.009 1.24
5 R Intraparietal Sulcus 37 −58 34 5.45 0.008 1.25
44 −55 38 5.38 0.010 1.23
Negative Regions
7 L Cuneus −19 −69 24 −5.45 0.008 1.25
6 R Frontal Eye Field 34 −9 52 −5.69 0.003 1.31
5 L Primary Motor Cortex −29 −23 62 −5.65 0.003 1.3