Figure 4.

Representative synthetic result of obviously abnormal fundus photographs and angiographies. Both CycleEBGAN and CycleGAN converted hard exudates into hyperfluorescence, whereas microaneurysms and microaneurysms were ignored. The simulated images generated by the 2 models are almost identical. While Pix2Pix showed excellent performance in transforming vascular leaking, it generated abnormal optic discs and vessels. CycleEBGAN = energy-based cycle-consistent adversarial networks, CycleGAN = cycle-consistent adversarial networks.