Table 3.
Construct Validity of Select QOL-B and NTM Symptoms Domains in Patients With MAC-PD
| Measure and HRQoL Domain | AFB Smear Results |
FEV1 % Predicted |
FVC % Predicted |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Positive (n = 86) | Negative (n = 117) | P Value | < 70 (n = 46) | ≥70 (n = 112) | P Value | < 70 (n = 20) | ≥ 70 (n =138) | P Value | |
| QOL-B | |||||||||
| Respiratory symptoms | 65.1 ± 17.0 | 64.0 ± 17.0 | .66 | 60.7 ± 17.3 | 67.1 ± 16.4 | .03 | 56.2 ± 17.0 | 66.6 ± 16.5 | .009 |
| Physical functioning | 55.6 ± 32.1 | 61.6 ± 33.1 | .20 | 51.8 ± 32.1 | 65.4 ± 30.9 | .01 | 44.8 ± 31.5 | 63.9 ± 31.1 | .01 |
| Vitality | 59.4 ± 14.4 | 58.6 ± 12.4 | .70 | 60.9 ± 13.8 | 57.7 ± 13.1 | .18 | 61.1 ± 11.7 | 58.3 ± 13.5 | .38 |
| Health perception | 46.8 ± 19.1 | 47.0 ± 16.6 | .96 | 48.9 ± 19.1 | 45.6 ± 17.9 | .31 | 57.1 ± 15.8 | 45.1 ± 18.2 | .006 |
| NTM symptoms | 79.7 ± 14.5 | 77.4 ± 17.5 | .33 | 79.2 ± 15.9 | 78.2 ± 17.1 | .73 | 76.8 ± 18.0 | 78.7 ± 16.6 | .64 |
Dara are presented as mean ± SD. Boldface values indicate statistical significance at P < .05. AFB = acid-fast bacillus; HRQOL = health-related quality of life; MAC-PD = Mycobacterium avium complex pulmonary disease; NTM = nontuberculous mycobacteria; QOL-B = Quality of Life-Bronchiectasis.