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Schematic of hydrogel crosslinking mechanisms. Norbornene-modified hyaluronic acid (HA) and β-cyclodextrin-modified HA were used to form thiolated covalent crosslinks and physical crosslinks with adamantanes, respectively. Thiol–ene click chemistry was used to tether thiolated adamantane moieties in addition to thiolated RGD peptides for cell adhesion.
