Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jul 6;11:e15577. doi: 10.7717/peerj.15577

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

©2023 Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

PMC Copyright notice

(A) circRNAs serve as an miRNA sponge to regulate the expression of target genes; (B) ElciRNAs bind to U1 snRNP to form a complex, which in turn binds to Pol II in the promoter region to regulate the transcriptional level of genes; ciRNAs can directly accumulate in the parental transcribed region to promote Pol II activity and regulate the expression of downstream genes; (C) circRNAs can interact with RBPs to regulate the function of related proteins; (D) circRNAs can translate into peptides or proteins.