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. 2023 Jul 9;15(7):e41594. doi: 10.7759/cureus.41594

Table 3. Prevalence of HLA-DQ2, HLA-DQ8, any HLA (either HLA-DQ2 or HLA-DQ8), and both HLA (HLA-DQ2 and HLA-DQ8) genotypes in patients with lipedema from our study and in the general population.

Percentages indicate the proportion of individuals within each group possessing the specific genotype. (p<0.0001, chi-squared=26.128, degrees of freedom=3, contingency coefficient=0.000337).

  Patients in our study with lipedema General population
HLA-DQ2 47.37% 41.20%
HLA-DQ8 22.11% 11.30%
Any HLA (HLA-DQ2 or HLA-DQ8) 61.05% 53.70%
Both HLAs (HLA-DQ2 and HLA-DQ8) 7.37% 1.2%