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. Author manuscript; available in PMC: 2023 Sep 15.
Published in final edited form as: Acta Biomater. 2022 Jul 31;150:111–127. doi: 10.1016/j.actbio.2022.07.051

Figure 9.

Figure 9.

(A) Representative images (single Z-slices) of the fluorescent dextran (white) diffusing through a MAP scaffold (green) over time. Diffusion profiles for (B) 3.4 wt% nanoporous gel, (C) MAP gel with non-lyo-microgels, and MAP gel with (D) 3.4 wt% lyo-microgels and (E) 5 wt% lyo-microgels are presented as the relative concentration of 10 kDa dextran (concentration normalized to initial concentration) over distance for 12 minutes. Representative profiles are for one gel for each condition. (F) Representative example of the non-linear curve fitting (black mesh) for the diffusion profile shown as the relative concentration across time and distance. (G) Estimated effective diffusion coefficient (Deff) of 10 kDa fluorescent Dex for each condition compared to the reported value of free diffusion in water (DW) represented by the dotted line. A one-way ANOVA with Tukey HSD was performed with significance reported at p < 0.05 (*), <0.01 (**), <0.005 (***), and <0.001 (****).