| Study | Reason for exclusion |
|---|---|
| Ackerman 1968 | Tetracycline was one of the studied antibiotics; nowadays it is not recommended for the age range in our protocol |
| Arroll 2008 | Review |
| Betend 1972 | Trial is not about undifferentiated acute respiratory infections |
| Bloomfield 2004 | Trial conducted in hospitalised children with respiratory syncytial virus infection |
| Bovier‐Lapierre 1971 | Trial is not about undifferentiated acute respiratory infections |
| Carr 1973 | There is no placebo or non‐treatment control group in this trial |
| Castello 1981 | Not a RCT |
| De Mattia 1986 | Comparison between 2 antibiotics. Ages of participants are not clearly stated |
| De Sario 1986 | Study is not about undifferentiated respiratory infections |
| Easton 2010 | Not a RCT |
| Gjelstad 2013 | It is an article about medical education |
| Gordon 1974 | Data about the effects of antibiotic compared to control in relieving symptoms, preventing complications or causing adverse events were not provided |
| Gronås 1971 | Trial is a comparison of 2 antibiotics for respiratory infections probably caused by Haemophilus influenzae |
| Guerrier 1972 | Ages of participants were outside our protocol age range |
| Gupta 1977 | Comparison among 3 antibiotics; there is no placebo or non‐treatment control group |
| Hardy 1956 | Data for participants in our protocol age range were not available |
| He 2006 | The entire text could not be accessed |
| Henness 1982 | Study is a comparison among antibiotics; there is no placebo or non‐treatment control group |
| Higashi 2014 | Ages of participants were outside our protocol age range |
| Kundu 1976 | Ages of participants were outside our protocol age range |
| Lake 1971 | Ages of participants were outside our protocol age range |
| Lexomboon 1971 | Data about the effects of antibiotics compared to control in relieving symptoms, preventing complications and causing adverse events in children included in our protocol age range were not available |
| Limson 1972 | Ages of participants were outside our protocol age range |
| Lines 1973 | Trial is a comparison between 2 antibiotics |
| Little 1997 | Ages of participants were outside our protocol age range |
| Maeda 1999 | Data for children included specifically in our protocol age range were not available |
| Masbernard 1979 | Ages of participants were outside our protocol age range |
| McGuinness 1986 | Study is a comparison among antibiotics; no placebo or non‐treatment control group |
| Newell 1970 | Trial is not about undifferentiated acute respiratory tract infection |
| Oggero 1985 | Trial is a comparison between 2 antibiotics |
| Pan 2000 | Ages of participants were outside our protocol age range |
| Price 1975 | Trial is not about undifferentiated acute respiratory tract infections |
| Ratjen 2013 | An article about cystic fibrosis |
| Reinert 1991 | Data for children up to 5 years of age were not available |
| Rentsch 1980 | Not a RCT. Ages of participants were outside our protocol age range |
| Roper 1970 | Ages of participants were outside our protocol age range |
| Taylor 1977 | Trial was not about undifferentiated respiratory infections. Laboratory tests were used to exclude children with infections of bacterial aetiology |
| Todd 1981 | There are insufficient data for the sample age range and for the outcomes that are the subject of this review |
| Varricchio 2006 | In this trial 2 antibiotics are compared; there was no non‐treatment or placebo control group |
| Varricchio 2008 | Trial about culture‐proven acute bacterial infection |
| Windorfer 1980 | Comparison between 2 antibiotics; no placebo or non‐treatment control group |
| Zwart 2003 | No subgroup analyses for our protocol age range |
| Zwart 2004 | Ages of participants were outside our protocol age range |
RCT: randomised controlled trial