TABLE 1.
Proportion of times mean volume obtained by sampling 5 or 10 glomeruli was within given range of that obtained by sampling 20 glomeruli.
| Magnification | Within given % of model mean) | Glomeruli sampled | Overall (n = 20) | FSGS (n = 10) | Controls (n = 10) |
|---|---|---|---|---|---|
| 40× | 5 | 5 | 36 (29, 44)% | 32 (26, 39)% | 40 (26, 55)% |
| 40× | 5 | 10 | 56 (47, 65)% | 51 (42, 61)% | 61 (43, 77)% |
| 40× | 5 | 15 | 80 (72, 86)% | 76 (67, 84)% | 83 (67, 92)% |
| 40× | 10 | 5 | 63 (53, 71)% | 59 (49, 68)% | 66 (47, 82)% |
| 40× | 10 | 10 | 84 (77, 89)% | 83 (74, 89)% | 85 (70, 93)% |
| 40× | 10 | 15 | 98 (96, 99)% | 97 (94, 99)% | 98 (96, 99)% |
| 40× | 25 | 5 | 95 (93, 97)% | 95 (90, 97)% | 96 (91, 99)% |
| 40× | 25 | 10 | 100 (100, 100)% | 100 (100, 100)% | 100 (100, 100)% |
| 40× | 25 | 15 | 100% | 100% | 100% |
| 100× | 5 | 5 | 37 (29, 46)% | 32 (25, 40)% | 42 (27, 58)% |
| 100× | 5 | 10 | 59 (50, 68)% | 54 (44, 63)% | 64 (46, 79)% |
| 100× | 5 | 15 | 80 (73, 86)% | 78 (69, 85)% | 82 (66, 92)% |
| 100× | 10 | 5 | 64 (54, 73)% | 60 (50, 70)% | 67 (47, 83)% |
| 100× | 10 | 10 | 85 (78, 90)% | 84 (76, 90)% | 85 (70, 93)% |
| 100× | 10 | 15 | 98 (97, 99)% | 98 (96, 99)% | 98 (96, 99)% |
| 100× | 25 | 5 | 96 (93, 97)% | 95 (91, 97)% | 96 (91, 98)% |
| 100× | 25 | 10 | 100 (100, 100)% | 100 (100, 100)% | 100 (100, 100)% |
| 100× | 25 | 15 | 100% | 100% | 100% |
Note: 1000 iterations of random sampling of 5 or 10 glomeruli. Only includes those with 20 glomeruli. Model mean = mean glomerular volume obtained by sampling 20 glomeruli.