Fig. 1.

Patient attrition. ^aClaims must have occurred within 365 days of each other. Only non-diagnostic claims were included; non-diagnostic claims are medical claims in which diagnosis codes reflect confirmed diagnoses rather than suspected diagnoses reported to justify diagnostic tests or procedures. ^bVOC claims were considered discrete events if they occurred ≥ 3 days apart from each other. BMT bone marrow transplant; HSCT hematopoietic stem cell transplant; SCD sickle cell disease; VOC vaso-occlusive crisis