Table 1.
Characteristics of patients seeking infertility treatment who responded to a survey on the acceptance of whole genome sequencing and gene editing of human embryos, stratified by year of survey completion.
| 2018 Questionnaire Respondents N=469 | 2021 Questionnaire Respondents N=172 | |
|---|---|---|
| Age (years) | 41 (37-44) | 38 (35-40) |
| Female | 297 (63) | 138 (80) |
| Self-reported ethnicity | ||
| Hispanic, Latino, or Spanish Origin | 25 (5) | 15 (9) |
| Self-reported race | ||
| American Indian/Alaska Native + Hawaii | 7 (2) | 1 (1) |
| Asian | 77 (16) | 28 (16) |
| Black/African American | 22 (5) | 4 (2) |
| White | 355 (76) | 132 (77) |
| No response | 8 (2) | 7 (4) |
| Education | ||
| Less than college | 83 (18) | 24 (14) |
| College graduate | 167 (36) | 73 (42) |
| Graduate school | 216 (46) | 73 (42) |
| No response | 3 (1) | 2 (1) |
| Political beliefs | ||
| Conservative | 51 (11) | 20 (12) |
| Moderate | 154 (33) | 56 (33) |
| Liberal | 214 (46) | 77 (45) |
| Other | 33 (7) | 18 (11) |
| No response | 17 (4) | 1 (1) |
| Religion | ||
| Agnostic or Atheist | 90 (19) | 22 (13) |
| Christian | 243 (52) | 91 (53) |
| Other (Buddhist, Hindu, Muslim, Jewish) | 93 (20) | 22 (13) |
| No affiliation | 21 (5) | 34 (20) |
| No response | 22 (5) | 3 (2) |
| Work in health care | 118 (25) | 57 (33) |
| Nulliparous (among female respondents) | 60 (20) | 19 (14) |
| History of miscarriage | 89 (56) | 30 (49) |
| Prior infertility treatment | 262 (56) | 95 (55) |
| In vitro fertilization (IVF) | 192 (73) | 75 (79) |
| Plan for preimplantation genetic testing | 199 (42) | 69 (40) |
| A lot or good amount of prior knowledge of gene editing | 53 (11) | 34 (20) |
| A lot or good amount of prior knowledge of whole genome sequencing | 41 (9) | 33 (19) |
Data presented as median (interquartile range) or n (%)