TABLE 4.
Bacterial and fungal distribution in microbial keratitis at other academic ophthalmology departments in the United States*
| Wilmer Eye Institute, Baltimore, MD | Massachusetts Eye & Ear Infirmary Boston, MA27,37 | Wills Eye Hospital, Philadelphia, PA2 | Bascom Palmer Eye Institute, Miami, FL30,36 | St. Louis University, St. Louis, MO20 | University of California, San Francisco25 | University of Pittsburgh 26 | Doheny Eye Institute, Los Angeles (faculty practice)21 | Los Angeles County Hospital-University of Southern California (public hospital)21 | |
|---|---|---|---|---|---|---|---|---|---|
| Most common bacterial isolate | Coagulase-negative Staphylococcus spp. (24.8%) | Coagulase-negative Staphylococcus spp. (45.5%) | Pseudomonas aeruginosa (24%) | Pseudomonas aeruginosa (26%) | Pseudomonas aeruginosa (26%) | Methicillin-susceptible Staphylococcus aureus (20%) | Pseudomonas aeruginosa (18.6%) | Coagulase-negative Staphylococcus spp. (41%) | Coagulase-negative Staphylococcus spp. (30%) |
| Most common fungal isolate in fungal keratitis | Candida spp. (45%) | Fusarium spp.10 (41%) | Candida spp. (% unavail) | Fusarium spp. (62%) | Fusarium spp. (35%) | --- | --- | Candida spp. (14%) | Candida spp. (29%) |
| Bacteria vs. fungi | 90% vs. 10% | --- | 85% vs. 15% | --- | 84% vs. 16% | --- | --- | 91% vs. 9% | 89% vs. 11% |
| Gram-positive vs. Gram-negative in bacterial keratitis | 69.5% vs 28.4% | 87% vs 13% | --- | 48% vs 50% | 59% vs. 41% | 65% vs 35% | 56% vs 44% | 70% vs 21% | 68% vs 21% |
| Pseudomonas aeruginosa prevalence in bacterial keratitis | 12% | 3% | 24% | 26% | 21% | 11% | 17% | 13% | 10% |
*
For proportions of bacterial keratitis in our study as well as other studies included for comparison, the number of cases of bacterial keratitis, rather than all cases of microbial keratitis, was used as the denominator.