Table 3.
Summary of findings for symptom burden measures
| Depression | Anxiety | |
|---|---|---|
| Overall symptom burden or distress | r=[0.49–0.68]; d=1.08 72,82,87,92 | d=1.35 82 |
| Number of symptoms endorsed | r=0.45 92 | no data available |
| Overall well-being | r=−[0.44–0.73] 69,77,82,85,87 | r=−[0.21–0.44] 69,77,82 |
| Intensity of specific physical symptoms: | ||
| Pain | r=[0.19–0.51] 67,69,77,78,82,85,87,92,93 No association79,90,92 |
r=[0.41–0.46] 67,69,77,82,91 No association87,90 |
| Lower energy, drowsiness or fatigue | r=[0.25–0.49] 67,69,77–79,82,85–87,90,92 No association78,81,82,90,92 |
r=[0.25–0.48] 67,69,82,86,90 No association90 |
| Gastrointestinal symptoms | r=[0.29–0.32] 67–69,77–79,85,91 No association86,87,97 |
r=[0.35–0.36] 67–69,77,86 No association90 |
| Dyspnea | r=[0.24–0.44] 67,69,77,78,85,92 No association79,87,90,92 |
r=0.21 69,77,82 No association90 |
| Poor appetite | r=[0.35–0.46] 67,69,77,82,84,85 No association87 |
r=0.24 67,82 |
| Insomnia | r=0.20 77,85,90 No association82,97 |
r=0.38 77,82,90 |
| Other symptoms | r=[0.21–0.34] 92 | no data available |