Table 2.
Self-reported and objectively measured activity during neoadjuvant therapy.
| Arm A | Arm B |
P-value for difference between Arms A and B** |
|
|---|---|---|---|
| Self-reported exercise (modified Godin questionnaire) † | |||
| n | 51 | 50 | |
| Mild-intensity exercise, mean weekly minutes ± SD | |||
| Baseline | 297.3 ± 699.5 | 135.0 ± 220.5 | 0.99 |
| Follow-up | 131.1 ± 212.3 | 155.6 ± 180.6 | 0.06 |
| Δ within group | −166.2 ± 727.8 | 20.6 ± 234.6 | 0.09 |
| P-value for Δ within group* | 0.65 | 0.23 | |
| Moderate-intensity exercise, mean weekly minutes ± SD | |||
| Baseline | 80.3 ± 112.9 | 126.2 ± 162.6 | 0.31 |
| Follow-up | 89.4 ± 124.6 | 115.7 ± 150.8 | 0.22 |
| Δ within group | 9.1 ± 147.8 | −10.5 ± 168.2 | 0.53 |
| P-value for Δ within group* | 0.98 | 0.95 | |
| Strenuous-intensity exercise, mean weekly minutes ± SD | |||
| Baseline | 33.2 ± 82.0 | 26.4 ± 60.4 | 0.75 |
| Follow-up | 17.9 ± 53.9 | 13.9 ± 27.9 | 0.40 |
| Δ within group | −15.3 ± 86.6 | −12.5 ± 54.2 | 0.85 |
| P-value for Δ within group* | 0.13 | 0.21 | |
| Moderate-to-strenuous exercise, mean weekly minutes ± SD | |||
| Baseline | 113.5 ± 141.3 | 152.6 ± 181.7 | 0.23 |
| Follow-up | 107.4 ± 160.4 | 129.6 ± 161.6 | 0.49 |
| Δ within group | −6.2 ± 172.2 | −23.0 ± 172.0 | 0.62 |
| P-value for Δ within group* | 0.29 | 0.49 | |
| Strength training, mean weekly sessions ± SD | |||
| Baseline | 1.4 ± 2.1 | 0.4 ± 1.0 | 0.003 |
| Follow-up | 1.5 ± 1.9 | 2.2 ± 1.8 | 0.06 |
| Δ within group | 0.1 ± 2.4 | 1.8 ± 1.8 | <0.001 |
| P-value for Δ within group* | 0.75 | <0.001 | |
| Activity tracker-measured physical activity during the preoperative period | |||
| n | 58 | 54 | |
| Valid wear day percentage, mean ± SD | 88.7 ± 13.0 | 86.1 ± 18.4 | 0.82 |
| Valid wear week percentage, mean ± SD | 90.8 ± 17.0 | 89.2 ± 19.2 | 0.95 |
| Daily steps, mean ± SD | 5349.4 ± 2226.5 | 5586.7 ± 2164.4 | 0.58 |
| Weekly sedentary minutes, mean ± SD | 6362.4 ± 1621.8 | 6427.3 ± 1191.6 | 0.86 |
| Weekly light activity minutes, mean ± SD | 1025.8 ± 448.5 | 920.4 ± 405.5 | 0.21 |
| Weekly fairly active minutes, mean ± SD | 75.3 ± 66.6 | 75.3 ± 65.9 | 0.87 |
| Weekly very active minutes, mean ± SD | 77.9 ± 85.4 | 84.5 ± 77.7 | 0.47 |
| Weekly active minutes, mean ± SD | 153.2 ± 135.6 | 159.8 ± 122.8 | 0.62 |
*
Wilcoxon signed rank test used due to non-normal variable distribution.
**
Wilcoxon signed rank test used for baseline and follow-up comparisons and activity-tracker variables due to non-normal variable distribution; independent t-test used for change score comparisons.
†
Follow-up time point assessed self-reported exercise throughout the study period.