Table 4.
Changes in patient-reported outcomes and body composition within arms and between arms.
| Outcome | Arm A | Arm B |
P-value for difference between Arm A and Arm B |
|---|---|---|---|
| Physical functioning (PROMIS score), mean ± SD | |||
| n | 44 | 45 | |
| Baseline | 47.6 ± 6.4 | 47.0 ± 6.1 | 0.67 |
| Follow-up | 47.2 ± 6.1 | 46.9 ± 7.7 | 0.84 |
| Δ within group | −0.4 ± 4.6 | −0.1 ± 5.3 | 0.79 |
| P-value for Δ within group | 0.56 | 0.87 | |
| Health-related quality of life (FACT-Hep score), mean ± SD | |||
| n | 45 | 46 | |
| Baseline | 139.6 ± 20.7 | 140.3 ± 20.5 | 0.86 |
| Follow-up | 141.6 ± 23.7 | 141.1 ± 23.7 | 0.93 |
| Δ within group | 2.0 ± 16.3 | 0.8 ± 19.6 | 0.75 |
| P-value for Δ within group | 0.41 | 0.78 | |
| Skeletal muscle index (cm2/m2), mean ± SD | |||
| Females | |||
| n | 26 | 22 | |
| Baseline | 41.1 ± 7.8 | 41.1 ± 5.1 | 0.99 |
| Follow-up | 41.0 ± 6.9 | 40.4 ± 6.5 | 0.76 |
| Δ within group | −0.04 ± 3.3 | −.6 ± 4.7 | 0.61 |
| P-value for Δ within group | 0.95 | 0.09 | |
| Males | |||
| n | 30 | 38 | |
| Baseline | 55.0 ± 10.3 | 50.8 ± 7.8 | 0.06 |
| Follow-up | 54.3 ± 8.6 | 49.5 ± 6.6 | 0.01 |
| Δ within group | −0.7 ± 5.9 | −1.3 ± 4.6 | 0.62 |
| P-value for Δ within group | 0.53 | 0.54 | |
| Skeletal muscle density (HU), mean ± SD | |||
| n | 56 | 60 | |
| Baseline | 38.0 ± 11.0 | 37.3 ± 7.7 | 0.71 |
| Follow-up | 38.4 ± 11.0 | 38.4 ± 8.8 | 0.99 |
| Δ within group | 0.5 ± 7.3 | 1.1 ± 7.2 | 0.63 |
| P-value for Δ within group | 0.64 | 0.24 |