Table 2:

Sleep Parameters on Intervention Nights

	Placebo vs. Suvorexant 10 mg	Placebo vs. Suvorexant 20 mg
NIGHT 1
Total Sleep Time (min)
Mean difference	−34.88	−50.47
95% CI	−97.77, 28.00	−114.6, 13.71
p-value	0.35	0.14
Sleep Efficiency (%)
Mean difference	−3.94	−7.65
95% CI	−11.91, 4.04	−15.79, 0.49
p-value	0.43	0.07
NREM Stage 2 (min)
Mean difference	−21.73	−25.71
95% CI	−79.59, 36.13	−84.77, 33.34
p-value	0.60	0.51
NREM Stage 3 (min)
Mean difference	−17.35	−11.27
95% CI	−54.99, 20.30	−49.69, 27.15
p-value	0.47	0.73
REM (min)
Mean difference	−5.50	−20.96
95% CI	−48.38, 37.38	−64.73, 22.80
p-value	0.94	0.45
NIGHT 2
Total Sleep Time (min)
Mean difference	−10.54	−38.71
95% CI	−88.42, 67.33	−116.6, 39.17
p-value	0.93	0.42
Sleep Efficiency (%)
Mean difference	−0.10	−5.26
95% CI	−10.39, 10.19	−15.55, 5.03
p-value	0.99	0.40
NREM Stage 2 (min)
Mean difference	−0.43	−9.89
95% CI	−61.92, 61.07	−71.38, 51.61
p-value	0.99	0.91
NREM Stage 3 (min)
Mean difference	−10.90	−3.49
95% CI	−52.16, 30.36	−44.75, 37.77
p-value	0.77	0.97
REM (min)
Mean difference	−2.30	−21.46
95% CI	−36.68, 32.09	−55.85, 12.93
p-value	0.98	0.27

Mg: milligrams; min: minutes; CI: confidence intervals; NREM: non-rapid eye movement; REM: rapid eye movement.

^*p-values corrected using Dunnett’s multiple comparison’s test