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. Author manuscript; available in PMC: 2024 Jun 1.
Published in final edited form as: Circ Genom Precis Med. 2023 Apr 11;16(3):216–223. doi: 10.1161/CIRCGEN.122.003772

Table 4.

Individual clinical variables nominally associated with accelerated aging (p<0.05)

Clinical measure Non-accelerated aging Accelerated aging Odds ratio (95% CI) p

Diastolic blood pressure (mmHg) 78.0 (9.7) 80.6 (10.7) 1.03 (1.0, 1.05) 0.04
Blood glucose (mg/dl) 107 (44) 123 (67) 1.01 (1.0, 1.01) 0.04
Mean corpuscular hemoglobin concentration (% RBC) 33.0 (0.8) 32.7 (0.9) 0.61 (0.44, 0.84) 0.003
Center subfield thickness (center 1mm) 263 (32) 254 (25) 0.99 (0.98, 1.0) 0.01

Results are presented as mean (SD) for each measure. Odds ratios (ORs) from a logistic regression model adjusted for sex. ORs >1 indicate an increase in accelerated aging with an increase in the clinical measure; ORs <1 indicate a decrease in accelerated aging with an increase in the clinical measure.

No results have false discovery rate (FDR) q-value< 0.1.

CI, confidence interval; RBC, red blood cell.