Table 5.
Multivariable Cox proportional hazards models for the associations of changes in lifestyle on all-cause mortality, breast cancer-mortality, and breast cancer recurrence in the Pathways Study.
| All-Cause Mortality | Breast Cancer-Specific Mortality | Breast Cancer Recurrence | ||||
|---|---|---|---|---|---|---|
| Concordance Level | # events | HRa (95%CI) | # events | HRa (95%CI) | # events | HRa (95%CI) |
| Maintained Lowb | 69 | 1.00 (–) | 24 | 1.00 (–) | 34 | 1.00 (–) |
| Maintained Partialc | 45 | 0.89 (0.61, 1.30) | 9 | 0.66 (0.30, 1.43) | 29 | 0.87 (0.52, 1.43) |
| Maintained Highd | 19 | 0.61 (0.37, 1.03) | 4 | 0.51 (0.17, 1.49) | 20 | 0.86 (0.49, 1.52) |
| Increasede | 57 | 0.91 (0.64, 1.31) | 17 | 0.98 (0.52, 1.86) | 39 | 0.89 (0.56, 1.42) |
| Decreasedf | 52 | 0.78 (0.54, 1.13) | 16 | 0.70 (0.37, 1.33) | 30 | 0.77 (0.47, 1.26) |
Abbreviations: CI, confidence intervals; HR, hazard ratio
Adjusts for age, tumor stage, ER status, chemotherapy, Herceptin, radiation, comorbidities, smoking status, income, and education level.
Participant in lowest category of guideline concordance (lifestyle score <7) at both baseline and 2 years post-diagnosis.
Participant in the middle category of guideline concordance (lifestyle score 8–10) at both baseline and 2 years post-diagnosis.
Participant in the highest category of guideline concordance (lifestyle score 11+) at both baseline and 2 years post-diagnosis.
Participant increased category of guideline concordance from baseline to 2 years post-diagnosis (e.g., participant went from being in the lowest category of concordance at baseline to being in the middle category 2 years post-diagnosis).
Participant decreased category of guideline concordance from baseline to 2 years post-diagnosis (e.g., participant went from being in the highest category of concordance at baseline to being in the middle category 2 years post-diagnosis).