Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(A) KIT secondary mutation detection significantly increased upon disease progression. (B) Representative subclonal evolution showing increased allele frequency in subpopulations with a KIT exon 13 V654A mutation, in parallel to primary clonal KIT exon 11 mutations. ABP, ATP-BP; AL, activation loop; BL, baseline; EOT, end-of-treatment; FC, fold change; VAF, variable allele frequency.
