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. Author manuscript; available in PMC: 2024 Jun 8.
Published in final edited form as: Annu Rev Chem Biomol Eng. 2023 Mar 14;14:217–241. doi: 10.1146/annurev-chembioeng-101121-084508

Figure 1. Key domains and antibody-targeted vulnerable sites in viral fusogen proteins from SARS-CoV-2, HIV-1, and influenza.

Figure 1.

For each virus, the cellular receptors are shown as well as structure of the fusogen with key domains and epitopes identified. Structures for influenza hemagglutinin H3 from PDB 4FNK, for HIV-1 envelope PDB 5CJX, for SARS-CoV-2 spike from PDB 7SXT.