Table 3.
Sexual history and substance use in study population, by at-risk determination based on HPV biomarker detection.
| N (%) | ||||
|---|---|---|---|---|
|
| ||||
| Characteristics | At-riska | Not at-riskb | P-valuec | Subset with HPV16 Biomarkers detectedd |
|
| ||||
| N=248 | N=860 | N=41 | ||
|
| ||||
| Lifetime number of people performed oral sex on | ||||
| ≤5 | 97 (39.4) | 371 (43.3) | 0.04 | 13 (32.5) |
| 6–10 | 54 (22.0) | 201 (23.4) | 9 (22.5) | |
| 11–50 | 64 (26.0) | 225 (26.3) | 13 (32.5) | |
| ≥51 | 31 (12.6) | 60 (7.0) | 5 (12.5) | |
| Marijuana use | ||||
| Never | 139 (56.0) | 459 (53.4) | 0.73 | 20 (48.8) |
| Former | 76 (30.7) | 285 (33.2) | 16 (39.0) | |
| Current | 33 (13.3) | 115 (13.4) | 5 (12.2) | |
| Cigarette use | ||||
| Never | 149 (60.1) | 512 (59.6) | 0.64 | 22 (53.6) |
| Former | 68 (27.4) | 255 (29.7) | 15 (36.6) | |
| Current | 31 (12.5) | 92 (10.7) | 4 (9.8) | |
| Ever e-cigarette use | 16 (6.5) | 76 (8.8) | 0.23 | 3 (7.3) |
| Current alcohol use | 145 (58.7) | 547 (63.7) | 0.15 | 28 (70.0) |
| Ever used an opioid pain reliever | 156 (72.2) | 516 (68.3) | 0.27 | 27 (84.4) |
|
| ||||
| Median (IQR) | Median (IQR) | |||
|
| ||||
| Lifetime number of people performed oral sex on | 8 (4,25) | 6 (4,15) | 0.14 | 9.0 (4.5,41.5) |
| Lifetime number of any sex partners | 15 (7,50) | 12 (7,30) | 0.051 | 24.5 (7.5,55) |
| Age first performed oral sex | 18 (16,21) | 18 (16,21) | 0.48 | 18.0 (16,21.5) |
| Sex-years | 4.5 (2.1,12.5) | 4.2 (2.0,8.8) | 0.45 | 7.2 (2.2,20.9) |
| Among ever marijuana users: Joint years | 3.7 (0.1, 23) | 0.4 (0, 4.3) | 0.01 | 3.2 (0.4, 25.3) |
| Among ever smokers: packyears | 15.8 (6.5, 32) | 13.4 (4.8, 25.2) | 0.37 | 15.6 (8.5, 26.6) |
| Among ever drinkers: Drink years | 10.3 (5.6, 44.4) | 14.7 (5.1, 38.4) | 0.25 | 7.5 (5.9,18.8) |
Among At-risk, N=17 had both positive rinse and blood, while 69 were categorized as positive based only on rinse, and 162 categorized as positive based only on blood.
Among those Not at-risk, N=758 were categorized based on both rinse and blood results being negative, 99 based on rinse only being negative (since blood not collected or results not yet available) and 3 based on blood only being negative (since rinse not collected or results not yet available).
P-value was tested for differences using chi-squared for categorical variables and K-sample equality-of-median tests for continuous variables
To be classified as positive in this group, needed to have either HPV16 oral DNA and/or HPV16 E6 seropositivity. 114 people who only had oral rinse (n=111) or only had blood (n=3) results for HPV16 were classified for this group by that single test.