Figure 9.

‘Synthetic’ data created in DataSim application using Simulation created basis set. Users set line width, digital resolution, SNR, phase, B0 shift, noise and macromolecule/baseline signals. Shown above is the main DataSim window: the full Spectral Settings tab with plot (left), Metabolite Signals tab truncated (middle), Macromolecule Signals tab truncated (right). Macromolecule/baseline signals are groups of Lorentzian or Gaussian lines. They are created separately to allow flexibility in adding nuisance signals.