Table 4.

Adjusted incidence rate ratios of asthma with recurrent exacerbations (ARE) by multivariate regression model

	aIRR (95% CI)	P value
Decade born
1990–1999	reference
2000–2009	1.62 (1.13, 2.32)	<0.01
2010–2017	0.76 (0.54, 1.08)	0.13
Child age (years)
10–19	reference
5–9	3.69 (2.89, 4.70)	<0.01
2–4	15.36 (12.09, 19.52)	<0.01
Child race and ethnicity
Non-Hispanic White	reference
Non-Hispanic Black	2.51 (2.10, 2.99)	<0.01
Hispanic White	1.30 (0.93, 1.82)	0.12
Hispanic Black	2.04 (1.22, 3.39)	<0.01
Other	1.67 (1.36, 2.07)	<0.01
Census region
West	reference
Northeast	3.34 (2.52, 4.43)	<0.01
Midwest	3.66 (2.75, 4.86)	<0.01
South	2.90 (2.16, 3.88)	<0.01
Child sex
Female	reference
Male	1.34 (1.16, 1.55)	<0.01
Parental history of asthma
None	reference
Either or both	2.90 (2.43, 3.46)	<0.01

Abbreviations: aIRR=adjusted incidence rate ratios; CI=confidence interval

N=17246. Model included a fixed effect for the research site location (aIRR: 1.00; 95% CI: 1.00–1.01) to control for any clustering effect. Children born during 2000–2009 had 2.12 times greater incidence of ARE than those born during 2010–2017 (95% CI: 1.77, 2.53). Other child race and ethnicity refers to all categories that do not fit into the mutually exclusive categories described. This includes children who list race as anything other than White or Black, list multiple races, or self-select “don’t know” or “other” on their forms.