Table 3.

The association of each individual comorbidity with in-hospital mortality ^a

	Logistic regression model				Elastic net model b
	Odds Ratio	95% CI		P-value	Odds Ratio
Congestive heart failure	1.743	1.691	1.796	<.0001	1.55
Peripheral vascular disease	1.098	1.062	1.136	<.0001	1.01
Chronic pulmonary disease	1.131	1.104	1.158	<.0001	1.03
Diabetes without chronic conditions	0.961	0.935	0.988	0.005	NA
Diabetes with chronic conditions	1.023	0.993	1.055	0.135	NA
Metastatic solid tumor	2.110	2.013	2.211	<.0001	2.05
Cardiac arrhythmia	1.797	1.755	1.84	<.0001	1.70
Valvular disease	0.898	0.866	0.932	<.0001	NA
Pulmonary circulation disorders	1.294	1.247	1.342	<.0001	1.19
Hypertension uncomplicated	0.689	0.667	0.712	<.0001	0.78
Hypertension complicated	0.765	0.739	0.793	<.0001	NA
Paralysis	1.598	1.513	1.687	<.0001	1.37
Other neurological disorders	2.17	2.117	2.223	<.0001	2.03
Hypothyroidism	0.853	0.829	0.878	<.0001	0.93
Renal failure	1.186	1.15	1.224	<.0001	1.05
Liver disease	1.944	1.873	2.018	<.0001	1.72
Peptic ulcer disease excluding bleeding	0.72	0.635	0.816	<.0001	NA
Lymphoma	1.542	1.443	1.648	<.0001	1.31
Solid Tumor without metastasis	1.454	1.396	1.515	<.0001	1.38
Rheumatoid arthritis/ collagen vascular diseases	0.921	0.871	0.973	0.0035	NA
Coagulopathy	1.779	1.725	1.835	<.0001	1.72
Obesity	0.708	0.682	0.735	<.0001	0.80
Weight loss	2.174	2.118	2.232	<.0001	2.14
Fluid and electrolyte disorders	2.599	2.537	2.663	<.0001	2.44
Deficiency anemia	0.686	0.65	0.724	<.0001	0.82
Alcohol abuse	0.697	0.656	0.741	<.0001	0.88
Drug abuse	0.525	0.484	0.57	<.0001	0.72
Psychoses	0.606	0.559	0.658	<.0001	0.82
Depression	0.655	0.632	0.678	<.0001	0.73

^aModels developed from the n=1,267,467 patient admissions training dataset.

^btraditional p-values are not directly available in elastic net model; CI=Confidence Interval; NA=Not available when elastic net model did not select the comorbidity as a substantial factor for predicting in-hospital mortality.