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. Author manuscript; available in PMC: 2024 Jul 1.
Published in final edited form as: Prog Neurobiol. 2023 May 4;226:102460. doi: 10.1016/j.pneurobio.2023.102460

Figure 4: Oligodendrocyte lineage marker mRNA+ cell counts increase in region-specific manner following ASPA re-expression at juvenile age.

Figure 4:

(A-C) Total summed PDGFRa, Olig2, and MBP mRNA+ cell counts for CTX, STR, CC, HC, TH, MB, CB, and BS brain regions. (D) Quantification of mRNA+ cells at 1-week post-treatment timepoint (7 weeks of age) and (E) at 4-week post ASPA re-expression timepoint (10 weeks of age). Two-way ANOVA with multi-comparison correction, CI 99%, mean ±SD, ns = not significant, * p<0.0332; ** p<0.0021, *** p<0.0002, **** p<0.0001. Abbr.: platelet-derived growth factor receptor alpha (PDGFRa), oligodendrocyte transcription factor 2 (Olig2), myelin basic protein (MBP).