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. Author manuscript; available in PMC: 2024 Jun 21.
Published in final edited form as: J Mater Chem B. 2023 Jun 21;11(24):5442–5459. doi: 10.1039/d3tb00066d

Figure 1.

Figure 1.

Three independent experiments (E1, E2, and E3) were performed with two batches of HA (B1 and B2) using U87 and LN229 mono-spheres encapsulated in Col-HA gels: A) experiment design and B) model configuration. (C, D) Sphere diameter, migration capacity, and adjusted migration distance (ad-distance) of C) U87 and D) LN229 mono-spheres are presented as average ± standard error. N = 4–8. (E, F) Principal component analysis (PCA) plots of E) U87 and F) LN229 mono-spheres shows separation of individual spheres in three experiment groups at the last day of culture (day 7 for U87 and day 9 for LN229).