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. Author manuscript; available in PMC: 2024 Jun 21.
Published in final edited form as: J Mater Chem B. 2023 Jun 21;11(24):5442–5459. doi: 10.1039/d3tb00066d

Figure 5.

Figure 5.

U87 (U) and LN229 (L) mono-sphere growth and migration in collagen-HA gels loaded with live (2MN-li) or fixed NHA (2MN-fi) at 2M cells/ml. A) Representative images of U87 or LN229 (green) mono-spheres and NHAs (red) at day 4, day 7, and day 9. NHA staining became weak over the culture duration, and therefore, was not captured after day 7. Scale bar = 200 μm. (B, C) Sphere diameter, migration capacity, and adjusted migration distance (ad-distance) of B) U87 and C) LN229 mono-spheres are presented as average ± standard error. N = 6~8. * is colour coded to the respective condition and suggests the group is statistically different from the control on that day. ◘ suggests that the live NHA and fixed NHA groups are significantly different from each other on that day. P < 0.05.