Table 3:
Summary of findings for different co-culture configurations. Arrow direction indicates change relative to the control (no astrocytes or no conditioned media).
| Culture Configuration | Sphere size | Migration capacity | Ad-distance | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GB-astrocyte multi-spheres Figure 2 |
U ↓ |
U ↓* |
U NS |
|||||||||
| GB mono-spheres in astrocyte-conditioned media Figure 3 |
U NS |
U NS |
U NS |
|||||||||
| GB mono-spheres with dispersed astrocytes Figure 4 |
U ↓ |
L ↑ |
U ↓ |
L ↑ |
U ↓* |
L ↑ |
||||||
| GB mono-spheres cultured with live vs. fixed dispersed astrocytes Figure 5 |
U/Li ↓ |
U/Fi ↑* |
L/Li ↑ |
L/Fi NS |
U/Li ↓* |
U/Fi ↑* |
L/Li ↑ |
L/Fi NS |
U/Li ↓* |
U/Fi ↑* |
L/Li ↑ |
L/Fi NS |
*
Indicates no statistically significant change until day 7 and/or after. NS = no significant change. U = U87 and L=LN229. Li = live astrocytes and F = fixed astrocytes.