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. 2023 Jun 26;14:1212149. doi: 10.3389/fmicb.2023.1212149

Table 4.

Polymorphism at the polycytidine tract and base 1,657 and Functionality of M1 and M12 mga among GAS genomes in the GenBank database.

M protein type genotype M1 M12
Polymorphism of mga at the polycytidine and base 1,654 in M1 and base 1,657 in M12 ac.1571C[8]/1654G or c.1574C[8]/1657G Frequency 150/158 25/106
AA No. of Mga 529 530
Functionality Yes Yes
c.1571C[7]/1654G or c.1574C[7]/1657G Frequency 3/158 3/106
AA No. of MGA 1,075 1,157
Functionality No No
c.1571C[6]/1654G or c.1574C[6]/1657G Frequency 5/158 38/106
AA No. of Mga 542 543
Functionality Yes Yes
c.1571C[7]/1654A or c.1574C[7]/1657A Frequency 0/158 40/106
AA No of Mga 543
Functionality Yes
a

The polycytidine tract with polymorphism starts at base 1,571 and 1,574 in M1 and M12 mga, respectively.