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. 2023 Jun 26;14:1200864. doi: 10.3389/fpsyt.2023.1200864

Table 3.

Random Forest analysis for the four groups: control subjects, FEP patients, SCZ patients, and ASD patients.

A. Random Forest statistics
Control FEP SCZ ASD
Sensitivity 92% 100% 38% 17%
Specificity 72% 85% 91% 100%
Pos. Pred. Value 69% 50% 60% 100%
Neg. Pred. Value 93% 100% 80% 83%
Balanced accuracy 82% 92% 64% 58%

Random Forest statistics over the four groups: Good classification (92% sensitivity, 72% specificity) for control subjects and for FEP patients (100% sensitivity, 85% specificity). ASD and SCZ groups showed high specificity (>90%) but low sensitivity (<38%).

Confusion Matrix of the four groups (after training on 70% of the group populations, N = 59): Correct classification in the validation subgroup (N = 30) of 11/12 control subject, 4/4 FEP patients, 3/8 SCZ patients, and 1/6 ASD patients. Thus, ASD patients were most difficult to classify/identify. See Supplementary Figure S6 for importance of the selected variables.