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. 2023 Jun 26;10:1206756. doi: 10.3389/fmed.2023.1206756

Table 4.

Genome based virulence gene screening of Klebsiella aerogenes (strain RD99) isolated from Dhaka, Bangladesh.

Virulence categories Virulence factors Related genes
Adherence Type 3 fimbriae mrkH, mrkI
Type I fimbriae fimA, fimB, fimC, fimD, fimE, fimF, fimG, fimH, fimI, fimK
CFA/I fimbriae (Escherichia) cfaB
Hemorrhagic E. coli pilus (HCP) (Escherichia) hofC
Antiphagocytosis Capsular polysaccharide wbjD/wecB
Efflux pump AcrAB acrA, acrB
Iron uptake Aerobactin iutA
Ent siderophore entA, entB, entC, entE, entF, entS, fepA, fepB, fepC, fepD, fepG, fes
Salmochelin IroB, iroC, iroD, iroE, iroN
Acinetobactin basG
Regulation RcsAB rcsA, rcsB
Secretion system T6SS-I clpV/tssH, hcp/tssD, impA/tssA, sciN/tssJ, tssF, tssG, vasE/tssK, vgrG/tssI, vipA/tssB, vipB/tssC
T6SS-II clpV, dotU, icmF, ompA
T6SS-III impA, impF
Flagella (cluster I) (Yersinia) flgA, flgB, flgC, flgD, flgE, flgF, flgG, flgH, flgI, flgJ, flgK, flgL, flgM, flgN, flhA, flhB, flhC, flhD, flhE, fliA, fliE, fliF, fliG, fliH, fliI, fliJ, fliL, fliM, fliN, fliP, fliQ, fliR, fliS, fliT,
Hcp secretion island-1 encoded type VI secretion system (H-T6SS) (Pseudomonas) clpV1, hcp1
Toxin Enterotoxin SenB/TieB senB
Heat-stable cytotonic enterotoxin ast
Fimbrial adherence determinants Bcf bcfB, bcfD, bcfE, bcfF, bcfG
Stc stcB, stcC
Invasion Flagella cheB, cheR, cheW, cheY, cheZ, motA
Magnesium uptake Mg2+ transport mgtB
Motility Flagella flaA, motB