Figure 4.

The three modified nucleotides of the S.cerevisiae mitochondrial 21S rRNA and their counterpart in E.coli 23S rRNA. Only the part of Domain V containing the three modified residues is represented according to the 2D structure drawn by Sirum-Connolly et al. (44). The positions of the three modified nucleotides are shown, the numbers of their counterparts in E.coli are indicated in brackets (43–45). Nucleotides are numbered starting from 5′-terminal. Helices are numbered according to Leffers et al. (50).