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. 2023 Jun 30;28(2):64–74. doi: 10.15430/JCP.2023.28.2.64

Table 7. IHC and endpoint RT-PCR for molecular subtyping of breast cancer (n = 41).

Molecular subtypes Based on IHC Based on endpoint RT-PCR
Using the expression of
ER, PR and HER2
Using St. Galen 2013 classification (ER, PR, HER2 & Ki-67) Using the expression of ER, PR and HER2
Frequency Frequency Frequency
Luminal-A 31 (75.6) 14 (34.1) 21 (51.2)
Luminal-B 7 (17.1) 24 (58.5) 8 (19.5)
TNBC 2 (4.9) 2 (4.9) 11 (26.8)
HER2+ 1 (2.4) 1 (2.4) 1 (2.4)

Values are presented as number (%). IHC, immunohistochemistry; RT-PCR, reverse transcription PCR; ER, estrogen receptor; PR, progesterone receptor; TNBC, triple negative breast cancer; HER2, human epidermal growth factor receptor 2; +, positive. The sum of the percentages does not equal 100% because of rounding.