Table 1.
Parameters Assessed as Possible Risk Factors for Failure. a
Group | Parameters |
---|---|
Demographic factors | Gender, age >75 y, body mass index >30, side of the affected foot |
Diabetic foot | Peripheral neuropathy, HbA1c >6%, Charcot foot, forefoot deformity, prior interventions |
Vascular status | Palpability of foot pulses, peripheral artery disease over stage 2 according to the Fontaine and the Rutherford systems |
Signs of infection | Ulcer probe-to-bone positive, signs of osteomyelitis on the standard radiograph, CRP >100 mg/L, white blood cell count >10 000/μL, duration of antibiotic treatment (in wk) |
Ulcer specification | Time since ulcer appearance (longer than 30 d), ulcer depth (deeper than subcutaneous), size of ulcer (>5 cm2), more than 1 ulcer |
Foot scores | Wagner score (>2), Infectious Diseases Society of America PEDIS score >2, Site, Ischemia, Neuropathy, Bacterial Infection and Depth (SINBAD) classification system grade (>3), Wound Ischemia and Foot Infection score (>4) |
Comorbidities | Renal insufficiency, creatinine in the blood (>200 μmol/L), arterial hypertension, arterial fibrillation, history of myocardial infarction, coronary artery disease, nicotine abuse |
Abbreviation: CRP, C-reactive protein; PEDIS, Perfusion, extent, depth, infection and sensation.
In parameters that are nonbinary, thresholds were defined.