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. 2023 Jul 8;8(3):24730114231182656. doi: 10.1177/24730114231182656

Table 1.

Parameters Assessed as Possible Risk Factors for Failure. a

Group Parameters
Demographic factors Gender, age >75 y, body mass index >30, side of the affected foot
Diabetic foot Peripheral neuropathy, HbA1c >6%, Charcot foot, forefoot deformity, prior interventions
Vascular status Palpability of foot pulses, peripheral artery disease over stage 2 according to the Fontaine and the Rutherford systems
Signs of infection Ulcer probe-to-bone positive, signs of osteomyelitis on the standard radiograph, CRP >100 mg/L, white blood cell count >10 000/μL, duration of antibiotic treatment (in wk)
Ulcer specification Time since ulcer appearance (longer than 30 d), ulcer depth (deeper than subcutaneous), size of ulcer (>5 cm2), more than 1 ulcer
Foot scores Wagner score (>2), Infectious Diseases Society of America PEDIS score >2, Site, Ischemia, Neuropathy, Bacterial Infection and Depth (SINBAD) classification system grade (>3), Wound Ischemia and Foot Infection score (>4)
Comorbidities Renal insufficiency, creatinine in the blood (>200 μmol/L), arterial hypertension, arterial fibrillation, history of myocardial infarction, coronary artery disease, nicotine abuse

Abbreviation: CRP, C-reactive protein; PEDIS, Perfusion, extent, depth, infection and sensation.

a

In parameters that are nonbinary, thresholds were defined.