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. 2023 Jul 10;13(30):20443–20456. doi: 10.1039/d3ra02579a

VEGFR-2 enzymatic target of compounds 3a, 3i and 3la.

Sample IC50 nM ± SD
3a 38.28 ± 1.79
3i 8.93 ± 0.61
3l 119 ± 4.1
Sorafenib 30 ± 1.39
a

“Values are expressed as the average of three independent replicates”. “IC50 values were calculated via the sigmoidal non-linear regression curve fitting of the percentage inhibition against the concentration of the compound”.