Antitumor parameters in the untreated, and treated SEC-bearing micea.
| Parameter | Treatments | ||||
|---|---|---|---|---|---|
| Normal control | SEC control | SEC + 3i | SEC + Sorafenib | ||
| Tumor potentiality | Tumor weight (mg) | — | 234.6 ± 13.2 | 83.2 ± 3.54 | 79.3 ± 4.63 |
| Tumor volume (mm3) | — | 369.8 ± 17.6 | 185.6 ± 18.9 | 164.3 ± 10.2 | |
| Tumor inhibition ratio (TIR%) | — | — | 49.8 ± 1.12 | 55.5 ± 1.31 | |
“Mean ± SD values of mice in each group (n = 6)”. “* Values are significantly different (P ≤ 0.05) between SEC control and normal group”, while “# values are significantly different (P ≤ 0.05) between treated SEC and SEC control mice using the un-paired test in GraphPad prism”. TIR% = C − T/C ×100.