Table 2.

Median (IQR) ABR for subjects who received prophylaxis for 4 or 5 years (subanalysis 1)

Treatment regimen	Type of ABR	Year 1	Year 2	Year 3	Year 4	Year 5
Subjects from B-LONG
WP		n = 21	n = 21	n = 21	n = 21	n = 21
	Overall	1.0 (0.0-2.1)	1.0 (0.0-2.2)	1.0 (1.0-3.0)	2.0 (0.0-5.0)	1.0 (0.0-4.0)
	Spontaneous	1.0 (0.0-1.1)	0.0 (0.0-1.0)	1.0 (0.0-2.0)	1.0 (0.0-2.0)	0.0 (0.0-1.2)
	Traumatic	0.0 (0.0-1.0)	0.0 (0.0-1.0)	0.0 (0.0-1.0)	0.0 (0.0-1.0)	0.0 (0.0-2.0)
	Joint	1.0 (0.0-1.1)	0.0 (0.0-1.0)	1.0 (0.0-2.1)	0.0 (0.0-2.0)	0.0 (0.0-2.3)
	Joint spontaneous	0.0 (0.0-1.0)	0.0 (0.0-1.0)	0.0 (0.0-1.0)	0.0 (0.0-0.0)	0.0 (0.0-1.0)
	Joint traumatic	0.0 (0.0-0.0)	0.0 (0.0-1.0)	0.0 (0.0-1.0)	0.0 (0.0-1.0)	0.0 (0.0-0.0)
Individualized IP		n = 17	n = 17	n = 17	n = 17	n = 17
	Overall	1.0 (0.0-3.0)	1.0 (1.0-3.0)	2.0 (1.0-5.0)	1.0 (0.0-1.0)	1.0 (0.0-2.0)
	Spontaneous	1.0 (0.0-2.3)	1.0 (0.0-1.0)	0.0 (0.0-1.0)	0.0 (0.0-1.0)	0.0 (0.0-1.0)
	Traumatic	0.0 (0.0-0.0)	1.0 (0.0-1.0)	1.0 (1.0-2.0)	0.0 (0.0-0.0)	0.0 (0.0-1.0)
	Joint	0.0 (0.0-3.0)	0.0 (0.0-1.0)	1.0 (0.0-4.0)	0.0 (0.0-1.0)	1.0 (0.0-1.3)
	Joint spontaneous	0.0 (0.0-2.3)	0.0 (0.0-1.0)	0.0 (0.0-1.0)	0.0 (0.0-1.0)	0.0 (0.0-1.0)
	Joint traumatic	0.0 (0.0-0.0)	0.0 (0.0-1.0)	0.0 (0.0-1.0)	0.0 (0.0-0.0)	0.0 (0.0-1.0)
Subjects from Kids B-LONG
WP		n = 10	n = 10	n = 10	n = 10
	Overall	2.0 (1.0-3.0)	2.0 (1.0-3.2)	0.5 (0.0-5.1)	0.0 (0.0-2.2)
	Spontaneous	0.0 (0.0-1.0)	0.0 (0.0-2.0)	0.0 (0.0-1.0)	0.0 (0.0-1.1)
	Traumatic	1.0 (0.0-2.0)	1.0 (0.0-2.0)	0.0 (0.0-1.0)	0.0 (0.0-1.1)
	Joint	0.5 (0.0-2.0)	1.0 (0.0-3.0)	0.0 (0.0-3.4)	0.0 (0.0-1.3)
	Joint spontaneous	0.0 (0.0-0.0)	0.0 (0.0-1.0)	0.0 (0.0-0.0)	0.0 (0.0-1.0)
	Joint traumatic	0.0 (0.0-1.0)	0.0 (0.0-1.0)	0.0 (0.0-1.0)	0.0 (0.0-0.0)