Table 2.

Output data of 2³ full factorial design of the developed DUL-loaded elastosomes.

Output	Responses
	Y1: E.E. ⁎ (%)	Y2: PS (nm)	Y3: ZP (mV)	Y4: Q0.5h (%)	Y5: Q8h (%)
R2	0.9678	0.9987	0.9643	0.9848	0.9947
Adjusted R2	0.9373	0.9977	0.9375	0.9735	0.9908
Predicted R2	0.8713	0.9948	0.8572	0.9395	0.979
Adequate precision	18.66	69.75	16.28	27.05	41.95
p value	0.0019	< 0.0001	0.0024	0.0004	< 0.0001
F value	40.13	1040.22	36.03	86.87	253.05
Press value	27.64	1030	51.34	10.54	8.86