Table 6.

Mean serum concentrations of lysophosphatidylcholines (LPC) analysed by Di-MS in kittens pre-gonadectomy (week −1) and post-gonadectomy (week 12) after supplementation with additional choline at 300 mg/kg BW^0·75 (CHOLINE, n 8) for 12 weeks compared with a control group (CONTROL, n 7) fed only the base diet (3310 mg choline/kg DM)

			CHOLINE (n 8)		CONTROL (n 7)
	Metabolites (µM)	Week	LSM	sem	LSM	sem	P Group	P Time	P Group × Time
LPC	LPC C14:0	–1	1·62	0·14	1·77	0·16	0·61	0·61	0·10
		12	1·79		1·45
	LPC C16:1	–1	2·94	0·36	3·26	0·39	0·34	0·89	0·06
		12	3·63		2·48
	LPC C16:0	–1	51·90	5·82	64·19	6·28	0·71	0·75	0·02
		12	65·14		47·29
	LPC C17:0	–1	2·33	0·27	3·01	0·29	0·93	0·91	0·02
		12	2·95		2·33
	LPC C18:2	–1	33·51	4·31	36·06	4·65	0·10	0·89	0·01
		12	44·97c		23·4d
	LPC C18:1	–1	22·20	2·87	26·06	3·10	0·29	0·84	0·01
		12	29·52c		17·63d
	LPC C18:0	–1	61·86	6·73	82·48	7·25	0·62	0·55	0·05
		12	83·83		70·15
	LPC C20:4	–1	5·78A	0·68	6·35	0·73	0·17	0·10	0·02
		12	8·67Bc		5·81d
	LPC C20:3	–1	2·55	0·20	2·93	0·22	0·82	0·19	0·04
		12	3·26c		2·77d
	LPC C24:0	–1	0·23	0·03	0·26	0·03	0·44	0·13	0·11
		12	0·33		0·26
	LPC C26:1	–1	0·06	0·01	0·085A	0·01	0·86	0·85	0·03
		12	0·09c		0·06Bd
	LPC C26:0	–1	0·10	0·01	0·12A	0·01	0·06	0·20	0·004
		12	0·13c		0·069Bd
	LPC C28:1	–1	0·18	0·02	0·20	0·02	0·10	0·63	0·03
		12	0·24c		0·16d
	LPC C28:0	–1	0·17	0·02	0·19	0·02	0·13	0·13	0·04
		12	0·18		0·12
Totals	LPC	–1	184·17A	21·40	228·39A	23·10	0·67	0·88	0·02
		12	243·45B		175·41B

LSM, least square means.

Rows or columns with no superscript indicates no significant differences for the measured parameter.

Down a column, different upper-case superscript letters (A, B) denote significant differences (P < 0·05) following a Tukey’s post hoc analysis within group (CHOLINE or CONTROL) over time (week −1 to week 12).

Across a row, different lower-case letters (c, d) denote significant differences (P < 0·05) following a Tukey’s post hoc analysis between groups (CHOLINE and CONTROL) at one time point (week −1 or week 12).