Table 1. Patient and Tumor Characteristics for Both Diagnostic and Surveillance Cohorts.
| Characteristic | No. (%) | |
|---|---|---|
| Diagnosis cohort (n = 163) | Surveillance cohort (n = 290) | |
| Age, median (IQR), y | 63 (56-68.5) | 63 (57-70) |
| Sex | ||
| Female | 21 (12.9) | 53 (18.3) |
| Male | 142 (87.1) | 237 (81.7) |
| Follow-up, median (IQR), mo | NA | 40.5 (17-67.5) |
| HPV-associated OPSCC | 152 (93.3) | 290 (100) |
| p16 positive | 150 (98.7) | 277 (95.5) |
| HPV PCR positive | 114 (75) | 246 (84.8) |
| HPV ISH positive | 16 (10.5) | 14 (4.8) |
| AJCC 8th edition tumor classification | ||
| T0 | 12 (7.5) | 14 (4.8) |
| T1 | 37 (23.1) | 107 (36.9) |
| T2 | 72 (44.4) | 121 (41.7) |
| T3 | 25 (15.4) | 27 (9.3) |
| T4 | 15 (9.3) | 21 (7.2) |
| AJCC 8th edition node classification | ||
| N0 | 19 (11.6) | 39 (13.4) |
| N1 | 104 (63.8) | 196 (67.5) |
| N2 | 35 (21.4) | 51 (17.6) |
| N3 | 4 (2.5) | 4 (1.4) |
| Treatment | ||
| Surgery alone | NA | 71 (24.5) |
| Surgery plus adjuvant | NA | 109 (37.6) |
| Radiation alone | NA | 7 (2.4) |
| Chemoradiation | NA | 54 (18.6) |
| Induction chemotherapy plus chemoradiation | NA | 49 (16.9) |
Abbreviations: AJCC, American Joint Committee on Cancer; HPV, human papillomavirus; ISH, in situ hybridization; NA, not applicable; OPSCC, oropharyngeal squamous cell carcinoma; PCR, polymerase chain reaction.