Table 3.

Agreement of Pleural cfDNA for Mutations With Pleural Cytology, Biopsy, and Plasma cfDNA

Testing Modality	Agreement of Pleural cfDNA in Samples With Positive Mutations	Overall Agreement of Pleural cfDNA	Overall Kappa Statistic of Agreement of Pleural cfDNA Kappa (95% CI)	Overall P Value for Agreement of Pleural cfDNA
Pleural cytology, n/N (%)	9/9 (100)	17/33 (51.5)	0.11 (−0.16, 0.39)	.44
Biopsy, n/N (%)	17/19 (89.4)	19/25 (76)	0.32 (−0.01, 0.65)	.21
Plasma cfDNA, n/N (%)	16/17 (94.1)	22/32 (68.8)	0.25 (−0.20, 0.70)	.06

cfDNA = cell-free DNA; n = concordant samples.