| Very young (applies to anthracyclines) or old age at exposure Combination of anti-cancer agents Prior exposure to anti-cancer agents Radiation therapy that included the heart or part of the heart in the irradiated volume Cumulative dose (applies to anthracyclines) Baseline LV dysfunction Cardiovascular risk factors (eg, hypertension, diabetes mellitus) Elevated troponin and/or NT-pro-BNP assays early following exposure |
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